Sbno1 Gene Summary [Rat]

Predicted to enable chromatin DNA binding activity and histone binding activity. Predicted to be involved in several processes, including negative regulation of neuroinflammatory response; positive regulation of neural precursor cell proliferation; and regulation of signal transduction. Predicted to be active in nucleus. Orthologous to human SBNO1 (strawberry notch homolog 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Sbno1
Official Name
strawberry notch homolog 1 [Source:RGD Symbol;Acc:1310005]
Ensembl ID
ENSRNOG00000001064
Bio databases IDs NCBI: 304470 Ensembl: ENSRNOG00000001064
Aliases strawberry notch homolog 1
Synonyms 9330180L10RIK, LOC283378, MOP3, mSno1, Sbno, Sno, strawberry notch 1, strawberry notch homolog 1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Sbno1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • C-terminal domain on Strawberry notch homolog
  • P-loop containing NTP hydrolase pore-1
  • Type III restriction enzyme, res subunit
  • N-terminal helicase domain of the DEAD-box helicase superfamily
  • enzyme
  • P-loop containing Nucleoside Triphosphate Hydrolases

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • non-insulin-dependent diabetes mellitus
  • schizophrenia
  • insomnia
  • osteoarthritis
  • venous thromboembolism
  • knee osteoarthritis
regulated by
  • Caco2 cells
role in cell
  • apoptosis
  • proliferation
  • JQ1-sensitivity

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Sbno1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • regulation of transcription, DNA-dependent

Cellular Component

Where in the cell the gene product is active
  • nucleus

Molecular Function

What the gene product does at the molecular level
  • chromatin DNA binding
  • histone binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.