Sbno1 Gene Summary [Mouse]
Predicted to enable chromatin DNA binding activity and histone binding activity. Involved in negative regulation of neuroinflammatory response; positive regulation of neural precursor cell proliferation; and regulation of signal transduction. Located in nucleus. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and liver. Orthologous to human SBNO1 (strawberry notch homolog 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Sbno1 |
| Official Name | strawberry notch 1 [Source:MGI Symbol;Acc:MGI:2384298] |
| Ensembl ID | ENSMUSG00000038095 |
| Bio databases IDs | |
| Aliases | strawberry notch 1 |
| Synonyms | 9330180L10RIK, LOC283378, MOP3, mSno1, Sbno, Sno, strawberry notch 1, strawberry notch homolog 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Sbno1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- C-terminal domain on Strawberry notch homolog
- P-loop containing NTP hydrolase pore-1
- Type III restriction enzyme, res subunit
- N-terminal helicase domain of the DEAD-box helicase superfamily
- enzyme
- P-loop containing Nucleoside Triphosphate Hydrolases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Sbno1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of transcription, DNA-dependent
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- chromatin DNA binding
- histone binding