Mx2 Gene Summary [Rat]
Predicted to enable GTP binding activity; GTPase activity; and microtubule binding activity. Involved in response to virus. Located in cytoplasm. Human ortholog(s) of this gene implicated in alopecia areata; avian influenza; liver disease; and prostate cancer. Orthologous to several human genes including MX1 (MX dynamin like GTPase 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mx2 |
| Official Name | MX dynamin like GTPase 2 [Source:RGD Symbol;Acc:628821] |
| Ensembl ID | ENSRNOG00000001963 |
| Bio databases IDs | |
| Aliases | MX dynamin like GTPase 2 |
| Synonyms | Mx2 + Mx3, Mx3, MX dynamin like GTPase 2 |
| Species | Rat, Rattus norvegicus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mx2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Dynamin GTPase effector domain
- GTP binding
- Dynamin central region
- GTPase
- enzyme
- P-loop containing Nucleoside Triphosphate Hydrolases
- Dynamin family
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- exocytic vesicle
- Nucleus
- nuclear pores