Ddx52 Gene Summary [Rat]

Enables RNA binding activity. Predicted to be involved in maturation of SSU-rRNA. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Ddx52
Official Name
DExD-box helicase 52 [Source:RGD Symbol;Acc:621743]
Ensembl ID
ENSRNOG00000002612
Bio databases IDs NCBI: 85432 Ensembl: ENSRNOG00000002612
Aliases DExD-box helicase 52
Synonyms 2700029C06Rik, ATP DEPENDENT RNA HELICASE, DExD-box helicase 52, HUSSY-19, ROK1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ddx52 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • DEAD/DEAH box helicase
  • Type III restriction enzyme, res subunit
  • helicase superfamily c-terminal domain
  • N-terminal helicase domain of the DEAD-box helicase superfamily
  • enzyme
  • DEAD-like helicases superfamily
  • Helicase conserved C-terminal domain
  • P-loop containing Nucleoside Triphosphate Hydrolases

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • colon cancer
  • liver cancer
  • lung cancer
regulated by
  • hydrogen peroxide
  • SIRT1 inhibitor III
  • intestinal epithelial cells
  • diphtheria toxin
role in cell
  • cellular reprogramming
  • pluripotency
  • processing in
  • autophagy in
  • autophagy

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nucleoplasm
  • nucleoli
  • interchromatin granule clusters

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Ddx52 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • maturation of SSU-rRNA

Cellular Component

Where in the cell the gene product is active
  • membrane
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • ATPase activity
  • ATP binding
  • RNA binding
  • RNA helicase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.