Ddx52 Gene Summary [Mouse]
Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and RNA helicase activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to be located in nucleolus. Is expressed in heart and limb. Orthologous to human DDX52 (DExD-box helicase 52). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ddx52 |
| Official Name | DExD box helicase 52 [Source:MGI Symbol;Acc:MGI:1925644] |
| Ensembl ID | ENSMUSG00000020677 |
| Bio databases IDs | |
| Aliases | DExD box helicase 52 |
| Synonyms | 2700029C06Rik, ATP DEPENDENT RNA HELICASE, DExD-box helicase 52, HUSSY-19, ROK1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ddx52 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- DEAD/DEAH box helicase
- Type III restriction enzyme, res subunit
- helicase superfamily c-terminal domain
- N-terminal helicase domain of the DEAD-box helicase superfamily
- enzyme
- DEAD-like helicases superfamily
- Helicase conserved C-terminal domain
- P-loop containing Nucleoside Triphosphate Hydrolases
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nucleoli
- interchromatin granule clusters
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ddx52 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maturation of SSU-rRNA
Cellular Component
Where in the cell the gene product is active
- membrane
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- ATP binding
- RNA binding
- RNA helicase activity