B4galt4 Gene Summary [Rat]
Predicted to enable N-acetyllactosamine synthase activity. Predicted to be involved in glycosylation; keratan sulfate proteoglycan biosynthetic process; and lactosylceramide biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Orthologous to human B4GALT4 (beta-1,4-galactosyltransferase 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | B4galt4 |
| Official Name | beta-1,4-galactosyltransferase 4 [Source:RGD Symbol;Acc:1307880] |
| Ensembl ID | ENSRNOG00000003114 |
| Bio databases IDs | |
| Aliases | beta-1,4-galactosyltransferase 4 |
| Synonyms | 9130402O08Rik, B4galt-IV, beta-1,4-galactosyltransferase 4, beta4Gal-T4, beta4GalT-IV, UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4, UDP-Gal:betaGlcNAc β 1,4-galactosyltransferase, polypeptide 4, UNQ552/PRO1109, β-1,4-galactosyltransferase 4 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat B4galt4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- galactosyltransferase
- N-terminal domain of galactosyltransferase
- N-terminal region of glycosyl transferase group 7
- enzyme
- protein binding
- UDP-glycosyltransferase
- N-acetyllactosamine synthase
- glycosyltransferase family A
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- keratocystic odontogenic tumor
- keratocystic odontogenic tumors
regulated by
- bone marrow-derived macrophages
- TTC39A-AS1
- dexamethasone
- Influenza A virus (A/Japan/305/57(H2N2))
regulates
- keratan sulfate
- lactosylceramide
- keratan sulfate proteoglycan
- membrane lipid derivative
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cellular membrane
- Golgi Apparatus
- Golgi membrane
- trans Golgi cisternae
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat B4galt4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- glycosylation
- carbohydrate metabolic process
- protein glycosylation
- keratan sulfate biosynthetic process
- lactosylceramide biosynthetic process
- membrane lipid metabolic process
Cellular Component
Where in the cell the gene product is active
- membrane
- Golgi membrane
- Golgi apparatus
- extracellular region
Molecular Function
What the gene product does at the molecular level
- protein binding
- N-acetyllactosamine synthase activity
- UDP-galactosyltransferase activity
- metal ion binding
- galactosyltransferase activity