NEWGENE_1565644 Gene Summary [Rat]
Predicted to be involved in cellular response to lipopolysaccharide and cellular response to muramyl dipeptide. Predicted to act upstream of or within maternal placenta development; maternal process involved in parturition; and regulation of growth hormone activity. Predicted to be located in nucleolus and nucleoplasm. Orthologous to human LDOC1 (LDOC1 regulator of NFKB signaling). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | NEWGENE_1565644 |
| Official Name | leucine zipper down-regulated in cancer 1 [Source:RGD Symbol;Acc:11505382] |
| Ensembl ID | ENSRNOG00000003409 |
| Bio databases IDs | |
| Aliases | leucine zipper down-regulated in cancer 1 |
| Synonyms | BCUR1, Gm366, LDOC1 regulator of NFKB signaling, LDOC1, regulator of NFKB signaling, Mar7, Mart7, NEWGENE 1565644, regulator of NFKB signaling, RGD1565644, RTL7, SIRH7 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Newgene_1565644 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Retrotransposon gag protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- survival
- early missed abortion
regulated by
regulates
- progesterone
- luciferase reporter gene
- synthetic promoter
- phosphatidylserine
role in cell
- apoptosis
- transmembrane potential
- cell viability
- proliferation
- response
- response by
- externalization in
- abnormality
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Newgene_1565644 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular response to lipopolysaccharide
- negative regulation of cell proliferation
- cellular response to muramyl dipeptide
- maternal process involved in parturition
- maternal placenta development
Cellular Component
Where in the cell the gene product is active
- nucleus
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding