Ldoc1 Gene Summary [Mouse]
Acts upstream of or within maternal placenta development; maternal process involved in parturition; and regulation of growth hormone activity. Predicted to be located in nucleolus and nucleoplasm. Is expressed in brain and ovary. Orthologous to human LDOC1 (LDOC1 regulator of NFKB signaling). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ldoc1 |
| Official Name | regulator of NFKB signaling [Source:MGI Symbol;Acc:MGI:2685212] |
| Ensembl ID | ENSMUSG00000057615 |
| Bio databases IDs | |
| Aliases | regulator of NFKB signaling |
| Synonyms | BCUR1, Gm366, LDOC1 regulator of NFKB signaling, LDOC1, regulator of NFKB signaling, Mar7, Mart7, NEWGENE 1565644, regulator of NFKB signaling, RGD1565644, RTL7, SIRH7 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ldoc1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Retrotransposon gag protein
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- survival
- early missed abortion
regulated by
regulates
- progesterone
- luciferase reporter gene
- synthetic promoter
- phosphatidylserine
role in cell
- apoptosis
- transmembrane potential
- cell viability
- proliferation
- response
- response by
- externalization in
- abnormality
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Ldoc1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular response to lipopolysaccharide
- negative regulation of cell proliferation
- cellular response to muramyl dipeptide
- maternal process involved in parturition
- maternal placenta development
Cellular Component
Where in the cell the gene product is active
- nucleus
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding