Gid4 Gene Summary [Rat]

The multiprotein Mediator complex is a coactivator required for activation of RNA polymerase II transcription by DNA bound transcription factors. The protein encoded by this gene is thought to be a subunit of the Mediator complex. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]

Details

Type
Protein Coding
Official Symbol
Gid4
Official Name
GID complex subunit 4 [Source:RGD Symbol;Acc:1588894]
Ensembl ID
ENSRNOG00000003847
Bio databases IDs NCBI: 687192 Ensembl: ENSRNOG00000003847
Aliases GID complex subunit 4
Synonyms 4933439F18Rik, C17orf39, GID complex subunit 4, GID complex subunit 4 homolog, GID complex subunit 4, VID24 homolog, VID2, VID24
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gid4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Vacuolar import and degradation protein

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • schizophrenia
  • major depression
  • systemic juvenile idiopathic arthritis
  • myocardial infarction
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Gid4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • proteasomal ubiquitin-dependent protein catabolic process

Cellular Component

Where in the cell the gene product is active
  • ubiquitin ligase complex

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.