Kap Gene Summary [Rat]
Predicted to be located in extracellular region. Orthologous to human TVP23C-CDRT4 (TVP23C-CDRT4 readthrough). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Kap |
| Official Name | kidney androgen regulated protein [Source:RGD Symbol;Acc:2947] |
| Ensembl ID | ENSRNOG00000005858 |
| Bio databases IDs | |
| Aliases | kidney androgen regulated protein |
| Synonyms | FKSG22, Image:518930, kidney androgen regulated protein |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Kap often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Kidney androgen-regulated
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- focal segmental glomerulosclerosis
- renal glucosuria
- hypertension
- streptozotocin-induced diabetic nephropathy
- proteinuria
regulated by
- dihydrotestosterone
- testosterone
- TGFB1
- flutamide
- androgen
- fulvestrant
- estrogen
- L-triiodothyronine
- cyclosporin A
- cisplatin
regulates
- CAT
- 8-hydroxy-deoxyguanosine diphosphate
- Cyp4a14
- glutathione peroxidase
- 8-epi-prostaglandin F2alpha
- malondialdehyde
- thiobarbituric acid reactive substances
- 20-hydroxyeicosatetraenoic acid
role in cell
- cell death
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- perinuclear region
- Endoplasmic Reticulum