Ms4a3 Gene Summary [Rat]

Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Orthologous to human MS4A3 (membrane spanning 4-domains A3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ms4a3
Official Name
membrane spanning 4-domains A3 [Source:RGD Symbol;Acc:1310598]
Ensembl ID
ENSRNOG00000036625
Bio databases IDs NCBI: 293753 Ensembl: ENSRNOG00000036625
Aliases membrane spanning 4-domains A3
Synonyms AC226593.1, CD20L, HTM4, membrane spanning 4-domains A3
Species
Rat, Rattus norvegicus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ms4a3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • CD20-like family

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • septic shock
regulated by
  • dexamethasone
  • tretinoin
  • corticosteroid
  • DNMT1
  • filgrastim
  • interferon alfacon-1
  • LY-2510924
  • TGME49_240060
  • TGM2
  • SLC38A4-AS1
regulates
role in cell
  • phosphorylation in
  • endocytosis in
  • G0/G1 phase transition

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • microsomal fraction
  • intracellular space
  • perinuclear region
  • cellular membrane
  • Nucleus
  • Plasma Membrane
  • specific granule membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Ms4a3 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • perinuclear region of cytoplasm
  • plasma membrane
  • specific granule membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.