Reg3a Gene Summary [Rat]
Predicted to enable oligosaccharide binding activity; peptidoglycan binding activity; and signaling receptor activity. Predicted to be involved in several processes, including antimicrobial humoral immune response mediated by antimicrobial peptide; negative regulation of keratinocyte differentiation; and positive regulation of keratinocyte proliferation. Predicted to be active in extracellular space. Used to study acute pancreatitis. Orthologous to human REG3A (regenerating family member 3 alpha) and REG3G (regenerating family member 3 gamma). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Reg3a |
| Official Name | regenerating islet-derived 3 alpha [Source:RGD Symbol;Acc:621401] |
| Ensembl ID | ENSRNOG00000006360 |
| Bio databases IDs | |
| Aliases | regenerating islet-derived 3 alpha |
| Synonyms | AV063448, Pap2, Pap II, regenerating islet-derived 3 alpha, regenerating islet-derived 3 α |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Reg3a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- C-type lectin (CTL)/C-type lectin-like (CTLD) domain
- Lectin C-type domain
- hormone
- identical protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space