Ankrd26 Gene Summary [Rat]
Predicted to act upstream of or within several processes, including negative regulation of fat cell differentiation; negative regulation of organ growth; and negative regulation of signal transduction. Predicted to be located in actin cytoskeleton and centrosome. Human ortholog(s) of this gene implicated in thrombocytopenia. Orthologous to several human genes including ANKRD26 (ankyrin repeat domain containing 26). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ankrd26 |
| Official Name | ankyrin repeat domain 26 [Source:RGD Symbol;Acc:1310736] |
| Ensembl ID | ENSRNOG00000006717 |
| Bio databases IDs | |
| Aliases | ankyrin repeat domain 26 |
| Synonyms | Ankrd26, ankyrin repeat domain 30A, ankyrin repeat domain containing 26, NY-BR-1, RGD1310736 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ankrd26 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mitotic checkpoint protein
- chromosome segregation protein SMC, primarily archaeal type
- Autophagy protein 16 (ATG16)
- Ankyrin repeats (many copies)
- exonuclease SbcC
- CCDC144C protein coiled-coil region
- rad50
- Synaptonemal complex protein 1 (SCP-1)
- Domain of unknown function (DUF3496)
- Ankyrin repeats (3 copies)
- Myosin tail
- helix-rich Mycoplasma protein
- Ankyrin repeat
- Alpha helical coiled-coil rod protein (HCR)
- chromosome segregation protein SMC, common bacterial type
- RecF/RecN/SMC N terminal domain
- RIM-binding protein of the cytomatrix active zone
- Septation ring formation regulator, EzrA
- HOOK protein coiled-coil region
- ankyrin repeats
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- actin cytoskeleton
- centrosome