ANKRD30A Gene Summary [Human]
This gene encodes a DNA-binding transcription factor that is uniquely expressed in mammary epithelium and the testis. Altered expression levels have been associated with breast cancer progression. [provided by RefSeq, Nov 2016]
Details
| Type | Protein Coding |
| Official Symbol | ANKRD30A |
| Official Name | ankyrin repeat domain 30A [Source:HGNC Symbol;Acc:HGNC:17234] |
| Ensembl ID | ENSG00000148513 |
| Bio databases IDs | |
| Aliases | ankyrin repeat domain 30A, breast cancer antigen NY-BR-1 |
| Synonyms | Ankrd26, ankyrin repeat domain 30A, ankyrin repeat domain containing 26, NY-BR-1, RGD1310736 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ANKRD30A often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Mitotic checkpoint protein
- chromosome segregation protein SMC, primarily archaeal type
- Autophagy protein 16 (ATG16)
- Ankyrin repeats (many copies)
- exonuclease SbcC
- CCDC144C protein coiled-coil region
- rad50
- Synaptonemal complex protein 1 (SCP-1)
- Domain of unknown function (DUF3496)
- Ankyrin repeats (3 copies)
- Myosin tail
- helix-rich Mycoplasma protein
- Ankyrin repeat
- Alpha helical coiled-coil rod protein (HCR)
- chromosome segregation protein SMC, common bacterial type
- RecF/RecN/SMC N terminal domain
- RIM-binding protein of the cytomatrix active zone
- Septation ring formation regulator, EzrA
- HOOK protein coiled-coil region
- ankyrin repeats
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- actin cytoskeleton
- centrosome