Gcfc2 Gene Summary [Rat]
Predicted to enable DNA binding activity. Predicted to be involved in spliceosomal complex assembly. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be part of U2-type post-mRNA release spliceosomal complex. Predicted to be active in nucleus. Orthologous to human GCFC2 (GC-rich sequence DNA-binding factor 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gcfc2 |
| Official Name | GC-rich sequence DNA-binding factor 2 [Source:RGD Symbol;Acc:1304792] |
| Ensembl ID | ENSRNOG00000006888 |
| Bio databases IDs | |
| Aliases | GC-rich sequence DNA-binding factor 2 |
| Synonyms | A130099G21, C2orf3, DNABF, GCF, GCF2, GC-rich sequence DNA-binding factor 2, RGD1304792, TCF9 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gcfc2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- protein binding
- GC-rich sequence DNA-binding factor-like protein
- Nineteen complex-related protein 2
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
- spliceosomes
- nucleoplasm
- nucleoli
- plasma
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Gcfc2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spliceosomal complex assembly
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
- nucleolus
- U2-type post-mRNA release spliceosomal complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein binding