Ttc9 Gene Summary [Rat]
Predicted to enable protein folding chaperone. Predicted to be involved in negative regulation of apoptotic process and protein folding. Predicted to act upstream of or within bone development. Predicted to be active in several cellular components, including cytosol; endomembrane system; and mitochondrial envelope. Human ortholog(s) of this gene implicated in opiate dependence. Orthologous to human TTC9 (tetratricopeptide repeat domain 9). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ttc9 |
| Official Name | tetratricopeptide repeat domain 9 [Source:RGD Symbol;Acc:1565985] |
| Ensembl ID | ENSRNOG00000007254 |
| Bio databases IDs | |
| Aliases | tetratricopeptide repeat domain 9 |
| Synonyms | 1700029M07RIK, KIAA0227, RGD1565985, tetratricopeptide repeat domain 9, TPR repeat protein 9, TTC9A |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ttc9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Tetratricopeptide repeats
- tetratricopeptide repeat
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ttc9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- bone development