Svbp Gene Summary [Rat]
Predicted to enable microtubule binding activity and peptidase activator activity. Predicted to be involved in several processes, including nervous system development; protein secretion; and regulation of protein metabolic process. Predicted to act upstream of or within negative regulation of endothelial cell migration. Predicted to be located in cytoplasm; cytoskeleton; and extracellular region. Predicted to be active in apical part of cell. Orthologous to human SVBP (small vasohibin binding protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Svbp |
| Official Name | small vasohibin binding protein [Source:RGD Symbol;Acc:1311232] |
| Ensembl ID | ENSRNOG00000007404 |
| Bio databases IDs | |
| Aliases | small vasohibin binding protein |
| Synonyms | 2410005K17Rik, CCDC23, NEDAHM, RGD1311232, small vasohibin binding protein |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Svbp often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- microtubule binding
- Coiled-coil domain-containing protein 23
- protein binding
- protease activator
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- apical compartment
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Svbp gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteolysis
- negative regulation of protein ubiquitination
- negative regulation of endothelial cell migration
- protein secretion
Cellular Component
Where in the cell the gene product is active
- cytoskeleton
- apical part of cell
- cytoplasm
- extracellular region
Molecular Function
What the gene product does at the molecular level
- peptidase activator activity
- protein binding
- microtubule binding