SVBP Gene Summary [Human]
Enables microtubule binding activity. Involved in axon development; proteolysis; and regulation of metallopeptidase activity. Acts upstream of or within negative regulation of endothelial cell migration; negative regulation of protein ubiquitination; and protein secretion. Located in apical part of cell. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SVBP |
| Official Name | small vasohibin binding protein [Source:HGNC Symbol;Acc:HGNC:29204] |
| Ensembl ID | ENSG00000177868 |
| Bio databases IDs | |
| Aliases | small vasohibin binding protein |
| Synonyms | 2410005K17Rik, CCDC23, NEDAHM, RGD1311232, small vasohibin binding protein |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SVBP often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- microtubule binding
- Coiled-coil domain-containing protein 23
- protein binding
- protease activator
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- apical compartment
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SVBP gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- proteolysis
- negative regulation of protein ubiquitination
- negative regulation of endothelial cell migration
- protein secretion
Cellular Component
Where in the cell the gene product is active
- cytoskeleton
- apical part of cell
- cytoplasm
- extracellular region
Molecular Function
What the gene product does at the molecular level
- peptidase activator activity
- protein binding
- microtubule binding