Ccdc47 Gene Summary [Rat]
Predicted to enable calcium ion binding activity; protein folding chaperone; and ribosome binding activity. Predicted to be involved in ERAD pathway; endoplasmic reticulum calcium ion homeostasis; and multi-pass transmembrane protein insertion into ER membrane. Predicted to act upstream of or within several processes, including ER overload response; calcium ion homeostasis; and endoplasmic reticulum organization. Predicted to be located in endoplasmic reticulum membrane and rough endoplasmic reticulum. Predicted to be part of multi-pass translocon complex and protein folding chaperone complex. Predicted to be active in endoplasmic reticulum. Orthologous to human CCDC47 (coiled-coil domain containing 47). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ccdc47 |
| Official Name | coiled-coil domain containing 47 [Source:RGD Symbol;Acc:1308813] |
| Ensembl ID | ENSRNOG00000009006 |
| Bio databases IDs | |
| Aliases | coiled-coil domain containing 47 |
| Synonyms | 2610204L23RIK, asp4, calumin, coiled-coil domain containing 47, D13Mgi22, GK001, MSTP041, RGD1308813, THNS |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ccdc47 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PAT complex subunit CCDC47
- calcium ion binding
- ribosome binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- Endoplasmic Reticulum
- endoplasmic reticulum membrane
- nuclear envelope
- rough endoplasmatic reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ccdc47 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- post-embryonic development
- osteoblast differentiation
- protein insertion into ER membrane
- endoplasmic reticulum calcium ion homeostasis
- protein folding
- ER overload response
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- rough endoplasmic reticulum membrane
- membrane
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- protein binding involved in protein folding
- ribosome binding
- calcium ion binding