Smcp Gene Summary [Rat]

Sperm mitochondria differ in morphology and subcellular localization from those of somatic cells. They are elongated, flattened, and arranged circumferentially to form a helical coiled sheath in the midpiece of the sperm flagellum. The protein encoded by this gene localizes to the capsule associated with the mitochondrial outer membranes and is thought to function in the organization and stabilization of the helical structure of the sperm's mitochondrial sheath. [provided by RefSeq, Jul 2008]

Details

Type
Protein Coding
Official Symbol
Smcp
Official Name
sperm mitochondria-associated cysteine-rich protein [Source:RGD Symbol;Acc:3069]
Ensembl ID
ENSRNOG00000009326
Bio databases IDs NCBI: 24899 Ensembl: ENSRNOG00000009326
Aliases sperm mitochondria-associated cysteine-rich protein
Synonyms HSMCSGEN1, MCS, MCSP, sperm mitochondria-associated cysteine-rich protein
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Smcp often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
  • KRTAP10-5
  • KRTAP10-3
  • CALCOCO2
  • KRTAP10-7
  • KRTAP4-7
  • PLSCR1
  • KRTAP4-11
  • KRTAP5-7
  • GOLGA2
  • NOTCH2NLA/NOTCH2NLB
disease
  • asthenozoospermia
regulated by
role in cell
  • binding
  • abnormal morphology
  • motility
  • penetration

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial outer membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Smcp gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • sperm motility
  • penetration of zona pellucida

Cellular Component

Where in the cell the gene product is active
  • mitochondrial membrane
  • cytoplasm
  • mitochondrion

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.