Smcp Gene Summary [Mouse]
Involved in flagellated sperm motility. Acts upstream of or within binding activity of sperm to zona pellucida and penetration of zona pellucida. Located in mitochondrion. Is expressed in testis. Orthologous to human SMCP (sperm mitochondria associated cysteine rich protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Smcp |
| Official Name | sperm mitochondria-associated cysteine-rich protein [Source:MGI Symbol;Acc:MGI:96945] |
| Ensembl ID | ENSMUSG00000074435 |
| Bio databases IDs | |
| Aliases | sperm mitochondria-associated cysteine-rich protein |
| Synonyms | HSMCSGEN1, MCS, MCSP, sperm mitochondria-associated cysteine-rich protein |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Smcp often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial outer membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Smcp gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sperm motility
- penetration of zona pellucida
Cellular Component
Where in the cell the gene product is active
- mitochondrial membrane
- cytoplasm
- mitochondrion
Molecular Function
What the gene product does at the molecular level
- protein binding