Details
| Type | Protein Coding |
| Official Symbol | Cyp4a3 |
| Official Name | cytochrome P450, family 4, subfamily a, polypeptide 3 [Source:RGD Symbol;Acc:631356] |
| Ensembl ID | ENSRNOG00000009741 |
| Bio databases IDs | |
| Aliases | cytochrome P450, family 4, subfamily a, polypeptide 3 |
| Synonyms | AI314743, Cyp4a11, Cyp4a14a, Cyp4a2, CYP4A3, CYPIVA3, cytochrome P450, family 4, subfamily a, polypeptide 14, cytochrome P450, family 4, subfamily a, polypeptide 2, cytochrome P450, family 4, subfamily a, polypeptide 3, LOC100365231, LOC108348356, Omega hydroxylase, P450-4A14, ω hydroxylase |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cyp4a3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cytochrome P450 (CYP) superfamily
- Cytochrome P450
- arachidonic acid 11,12-epoxygenase
- reduced flavin or flavoprotein:oxygen oxidoreductase
- fatty acid binding
- leukotriene-B4 20-monooxygenase
- CH-OH group:NAD or NADP oxidoreductase
- arachidonic acid binding
- enzyme
- arachidonic acid epoxygenase
- alkane 1-monooxygenase
- arachidonic acid monooxygenase
Pathways
Biological processes and signaling networks where the Cyp4a3 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- diabetic nephropathy
- nonalcoholic fatty liver disease
- proteinuria
- renal fibrosis
- hepatic fibrosis
role in cell
- synthesis in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- Extracellular Space
- endoplasmic reticulum membrane
- apical membrane