Srsf4 Gene Summary [Rat]
Enables sequence-specific mRNA binding activity. Involved in response to insulin. Predicted to be located in nuclear speck. Predicted to be active in cytoplasm and nucleus. Orthologous to human SRSF4 (serine and arginine rich splicing factor 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Srsf4 |
| Official Name | serine and arginine rich splicing factor 4 [Source:RGD Symbol;Acc:1561347] |
| Ensembl ID | ENSRNOG00000010007 |
| Bio databases IDs | |
| Aliases | serine and arginine rich splicing factor 4 |
| Synonyms | 5730499P16Rik, MNCb-2616, RGD1561347, serine and arginine-rich splicing factor 4, SFRS4, SRP75 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Srsf4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- RNA recognition motif (RRM) superfamily
- RNA recognition motif
- mRNA binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- spliceosomes
- nucleoplasm
- interchromatin granule clusters
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Srsf4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA splicing, via transesterification reactions
- RNA splicing
- response to insulin stimulus
- negative regulation of nuclear mRNA splicing, via spliceosome
- mRNA processing
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- nucleus
- nuclear speck
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA binding