Slc7a10 Gene Summary [Rat]

Predicted to enable L-amino acid transmembrane transporter activity and neutral L-amino acid transmembrane transporter activity. Predicted to be involved in negative regulation of brown fat cell differentiation; neutral amino acid transport; and positive regulation of glycinergic synaptic transmission. Located in apical dendrite and neuronal cell body. Orthologous to human SLC7A10 (solute carrier family 7 member 10). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Slc7a10
Official Name
solute carrier family 7 member 10 [Source:RGD Symbol;Acc:621672]
Ensembl ID
ENSRNOG00000010938
Bio databases IDs NCBI: 114518 Ensembl: ENSRNOG00000010938
Aliases solute carrier family 7 member 10
Synonyms AL024237, ASC1, D7Bwg0847e, HASC-1, solute carrier family 7 (cationic amino acid transporter, y+ system), member 10, solute carrier family 7 member 10
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Slc7a10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • amino acid permease (GABA permease)
  • amino acid permease
  • L-type amino acid transporter
  • protein binding
  • serine transporter
  • transporter
  • neutral amino acid transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Huntington disease
  • osteoporosis
regulated by
regulates
  • L-phenylalanine
  • L-leucine
  • D-serine
  • beta-alanine
  • L-histidine
  • L-isoleucine
  • L-cysteine
  • L-methionine
  • L-serine
  • L-aspartic acid
role in cell
  • differentiation
  • accumulation in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cellular membrane
  • perikaryon
  • apical processes

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Slc7a10 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • glycine transport
  • neutral amino acid transport
  • L-serine transport
  • positive regulation of synaptic transmission, glycinergic
  • amino acid transport
  • D-alanine transport
  • amino acid transmembrane transport
  • D-serine transport

Cellular Component

Where in the cell the gene product is active
  • membrane
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • L-amino acid transmembrane transporter activity
  • protein binding
  • neutral amino acid transmembrane transporter activity
  • L-serine transmembrane transporter activity

Gene-Specific Assays for Results You Can Trust

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