SLC7A10 Gene Summary [Human]
SLC7A10, in association with 4F2HC (SLC3A2; MIM 158070), mediates high-affinity transport of D-serine and several other neutral amino acids (Nakauchi et al., 2000 [PubMed 10863037]).[supplied by OMIM, Mar 2008]
Details
| Type | Protein Coding |
| Official Symbol | SLC7A10 |
| Official Name | solute carrier family 7 member 10 [Source:HGNC Symbol;Acc:HGNC:11058] |
| Ensembl ID | ENSG00000130876 |
| Bio databases IDs | |
| Aliases | solute carrier family 7 member 10 |
| Synonyms | AL024237, ASC1, D7Bwg0847e, HASC-1, solute carrier family 7 (cationic amino acid transporter, y+ system), member 10, solute carrier family 7 member 10 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SLC7A10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- amino acid permease (GABA permease)
- amino acid permease
- L-type amino acid transporter
- protein binding
- serine transporter
- transporter
- neutral amino acid transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- perikaryon
- apical processes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SLC7A10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- glycine transport
- neutral amino acid transport
- L-serine transport
- positive regulation of synaptic transmission, glycinergic
- amino acid transport
- D-alanine transport
- amino acid transmembrane transport
- D-serine transport
Cellular Component
Where in the cell the gene product is active
- membrane
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- L-amino acid transmembrane transporter activity
- protein binding
- neutral amino acid transmembrane transporter activity
- L-serine transmembrane transporter activity