Cep295 Gene Summary [Rat]
Predicted to enable microtubule binding activity. Predicted to be involved in several processes, including centriole replication; positive regulation of protein acetylation; and regulation of centrosome duplication. Predicted to be located in cytoplasm and mitotic spindle microtubule. Predicted to be active in centriole; centrosome; and cytosol. Orthologous to human CEP295 (centrosomal protein 295). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cep295 |
| Official Name | centrosomal protein 295 [Source:RGD Symbol;Acc:1311723] |
| Ensembl ID | ENSRNOG00000010999 |
| Bio databases IDs | |
| Aliases | centrosomal protein 295 |
| Synonyms | 5830418K08Rik, 5832426L23Rik, centrosomal protein 295, Gm1131, KIAA1731, LOC100360419, LOC100365060, LOC100506644, RGD1311723, SCKL11 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cep295 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- microtubule binding
- ALMS motif
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytoskeleton
- Plasma Membrane
- centrosome
- centriole
- cytosol
- spindle fibers
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cep295 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- centriole replication
- positive regulation of centrosome duplication
- regulation of centriole replication
Cellular Component
Where in the cell the gene product is active
- centrosome
- cytoskeleton
- cytoplasm
- centriole
- cytosol
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- microtubule binding