Cipc Gene Summary [Rat]
Predicted to be involved in negative regulation of DNA-templated transcription and negative regulation of circadian rhythm. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be active in nucleus. Orthologous to human CIPC (CLOCK interacting pacemaker). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cipc |
| Official Name | CLOCK-interacting pacemaker [Source:RGD Symbol;Acc:1309492] |
| Ensembl ID | ENSRNOG00000011111 |
| Bio databases IDs | |
| Aliases | CLOCK-interacting pacemaker |
| Synonyms | 2310044G17Rik, AI853744, CLOCK-interacting pacemaker, CLOCK interacting protein, circadian, KIAA1737, RGD1309492 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cipc often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Clock interacting protein circadian
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- hepatocellular carcinoma
- epithelial cancer
- liver cancer
- squamous cell cancer
- myelodysplastic syndrome
- asthma
- Huntington disease
- ulcerative colitis
- glioblastoma
- glioblastoma cancer
regulated by
- cigarette smoke
- gentamicin
- SPP1
regulates
role in cell
- phosphorylation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cipc gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- rhythmic process
- negative regulation of transcription, DNA-dependent
- negative regulation of circadian rhythm
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding