CIPC Gene Summary [Human]
Predicted to be involved in negative regulation of circadian rhythm and negative regulation of transcription, DNA-templated. Located in cytosol; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | CIPC |
| Official Name | CLOCK interacting pacemaker [Source:HGNC Symbol;Acc:HGNC:20365] |
| Ensembl ID | ENSG00000198894 |
| Bio databases IDs | |
| Aliases | CLOCK interacting pacemaker, CLOCK-interacting protein, circadian |
| Synonyms | 2310044G17Rik, AI853744, CLOCK-interacting pacemaker, CLOCK interacting protein, circadian, KIAA1737, RGD1309492 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human CIPC often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Clock interacting protein circadian
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- hepatocellular carcinoma
- epithelial cancer
- liver cancer
- squamous cell cancer
- myelodysplastic syndrome
- asthma
- Huntington disease
- ulcerative colitis
- glioblastoma
- glioblastoma cancer
regulated by
- cigarette smoke
- gentamicin
- SPP1
regulates
role in cell
- phosphorylation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human CIPC gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- rhythmic process
- negative regulation of transcription, DNA-dependent
- negative regulation of circadian rhythm
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytosol
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding