Layn Gene Summary [Rat]
Predicted to enable hyaluronic acid binding activity. Predicted to be located in membrane. Orthologous to human LAYN (layilin). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Layn |
| Official Name | layilin [Source:RGD Symbol;Acc:1564444] |
| Ensembl ID | ENSRNOG00000011228 |
| Bio databases IDs | |
| Aliases | layilin |
| Synonyms | E030012M19Rik, Gm511, layilin, RGD1564444 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Layn often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- extracellular domain
- TMEM154 protein family
- C-type lectin (CTL)/C-type lectin-like (CTLD) domain
- Lectin C-type domain
- protein binding
- hyaluronic acid binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- neoplasia
- early missed abortion
- bipolar disorder
- endometrial cancer
role in cell
- expression in
- production in
- killing
- accumulation
- inactivation
- adhesion
- killing by
- activation in
- inactivation in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- ruffle
- cell surface
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Layn gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- focal adhesion
- membrane
- ruffle
- cell surface
Molecular Function
What the gene product does at the molecular level
- hyaluronic acid binding
- carbohydrate binding