Slc7a9 Gene Summary [Rat]
Enables amino acid transmembrane transporter activity. Involved in amino acid transport. Located in plasma membrane. Human ortholog(s) of this gene implicated in cystinuria. Orthologous to human SLC7A9 (solute carrier family 7 member 9). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Slc7a9 |
| Official Name | solute carrier family 7 member 9 [Source:RGD Symbol;Acc:619905] |
| Ensembl ID | ENSRNOG00000012344 |
| Bio databases IDs | |
| Aliases | solute carrier family 7 member 9 |
| Synonyms | BAT1, CSNU3, Glycoprotein-associated amino acid transporter, solute carrier family 7 (cationic amino acid transporter, y+ system), member 9, solute carrier family 7 member 9 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Slc7a9 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- amino acid permease
- antiporter
- L-type amino acid transporter
- protein binding
- basic amino acid transporter
- cationic amino acid transport permease
- protein heterodimerization
- peptide antigen binding
- amino acid transporter
- transporter
- neutral amino acid transporter
- cystine transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- chronic kidney disease
- gout
- hydronephrosis
- cystinuria
- aminoaciduria
- interstitial nephritis
- crystalluria
- hereditary disorder
- lysinuria
- diabetes mellitus
regulated by
- dihydrotestosterone
- apatinib
- growth hormone
- heavy metal
regulates
- L-cystine
- amino acids
- neutral amino acid
- protein-protein complex
role in cell
- autophagy
- autophagy in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- membrane fraction
- cellular membrane
- apical membrane
- brush border
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Slc7a9 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- macromolecular complex assembly
- neutral amino acid transport
- L-cystine transport
- amino acid transmembrane transport
Cellular Component
Where in the cell the gene product is active
- brush border membrane
- plasma membrane
- apical plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- peptide antigen binding
- protein heterodimerization activity
- antiporter activity
- neutral amino acid transmembrane transporter activity
- L-cystine transmembrane transporter activity