Hdac1l Gene Summary [Rat]
Predicted to enable histone deacetylase activity. Predicted to be involved in heterochromatin formation. Predicted to be part of NuRD complex. Orthologous to human HDAC1 (histone deacetylase 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Hdac1l |
| Official Name | histone deacetylase 1-like [Source:RGD Symbol;Acc:619975] |
| Ensembl ID | ENSRNOG00000013695 |
| Bio databases IDs | |
| Aliases | histone deacetylase 1-like |
| Synonyms | Histone deacetylase 1-like |
| Species | Rat, Rattus norvegicus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Hdac1l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- enzyme
- Arginase-like and histone-like hydrolases
Pathways
Biological processes and signaling networks where the Hdac1l gene in rat plays a role, providing insight into its function and relevance in health or disease.
- Bladder Cancer Signaling
- Calcium Signaling
- Calcium-induced T Lymphocyte Apoptosis
- Chronic Myeloid Leukemia Signaling
- Cyclins and Cell Cycle Regulation
- DNA Methylation and Transcriptional Repression Signaling
- Glioma Signaling
- Hereditary Breast Cancer Signaling
- Huntington's Disease Signaling
- Molecular Mechanisms of Cancer
- NF-κB Signaling
- Non-Small Cell Lung Cancer Signaling
- Nur77 Signaling in T Lymphocytes
- Ovarian Cancer Signaling
- Pancreatic Adenocarcinoma Signaling
- Prostate Cancer Signaling
- Role of NFAT in Cardiac Hypertrophy
- Small Cell Lung Cancer Signaling
- Telomerase Signaling
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- nuclear fraction
- detergent-soluble fraction