Semg1 Gene Summary [Rat]
Predicted to enable zinc ion binding activity. Predicted to be involved in several processes, including negative regulation of flagellated sperm motility; positive regulation of serine-type endopeptidase activity; and sperm capacitation. Predicted to act upstream of or within fertilization. Predicted to be located in acrosomal vesicle and extracellular space. Predicted to be part of protein-containing complex. Orthologous to several human genes including SEMG1 (semenogelin 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Semg1 |
| Official Name | semenogelin 1 [Source:RGD Symbol;Acc:3790] |
| Ensembl ID | ENSRNOG00000013776 |
| Bio databases IDs | |
| Aliases | semenogelin 1 |
| Synonyms | RATSVPIIA, RWB, semenogelin 1, Svp1, SVPIIA, Svs2, SVS2P, Svs2p2, SvsII |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Semg1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protease binding
- zinc ion binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- acrosome