Svs2 Gene Summary [Mouse]
Predicted to enable protease binding activity and zinc ion binding activity. Acts upstream of or within fertilization and sperm capacitation. Located in acrosomal vesicle. Is expressed in alimentary system; bladder; and male reproductive gland or organ. Orthologous to human SEMG1 (semenogelin 1) and SEMG2 (semenogelin 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Svs2 |
| Official Name | seminal vesicle secretory protein 2 [Source:MGI Symbol;Acc:MGI:1858275] |
| Ensembl ID | ENSMUSG00000040132 |
| Bio databases IDs | |
| Aliases | seminal vesicle secretory protein 2 |
| Synonyms | RATSVPIIA, RWB, semenogelin 1, Svp1, SVPIIA, Svs2, SVS2P, Svs2p2, SvsII |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Svs2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protease binding
- zinc ion binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Extracellular Space
- acrosome