Smndc1 Gene Summary [Rat]

Predicted to enable RNA binding activity. Predicted to be involved in RNA splicing; apoptotic process; and mRNA processing. Predicted to be located in Cajal body; cytoplasm; and nuclear speck. Predicted to be part of spliceosomal complex. Predicted to be active in nucleus. Orthologous to human SMNDC1 (survival motor neuron domain containing 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Smndc1
Official Name
survival motor neuron domain containing 1 [Source:RGD Symbol;Acc:1309151]
Ensembl ID
ENSRNOG00000014833
Bio databases IDs NCBI: 287768 Ensembl: ENSRNOG00000014833
Aliases survival motor neuron domain containing 1
Synonyms 2410004J23RIK, SMNR, SPF30, survival motor neuron domain containing 1, TDRD16C
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Smndc1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • Tudor domain superfamily

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
regulated by
  • lipopolysaccharide
  • imatinib
  • arsenic trioxide
  • EP4-D
  • fingolimod
  • histone H3
  • RNase
  • N(G)-monomethyl-D-arginine
  • DAP3
regulates
role in cell
  • expression in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • nuclear fraction
  • spliceosomes
  • nucleoplasm
  • interchromatin granule clusters
  • nuclear speckles
  • Cajal bodies

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Smndc1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • RNA splicing, via transesterification reactions
  • apoptotic process
  • mRNA processing

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • cytoplasm
  • nuclear speck
  • Cajal body
  • spliceosomal complex
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.