Pgk2 Gene Summary [Rat]
Predicted to enable ADP binding activity; ATP binding activity; and phosphoglycerate kinase activity. Predicted to be involved in gluconeogenesis and glycolytic process. Predicted to act upstream of or within flagellated sperm motility. Predicted to be located in cilium. Predicted to be active in cytosol and sperm fibrous sheath. Orthologous to human PGK2 (phosphoglycerate kinase 2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pgk2 |
| Official Name | phosphoglycerate kinase 2 [Source:RGD Symbol;Acc:1306627] |
| Ensembl ID | ENSRNOG00000013600 |
| Bio databases IDs | |
| Aliases | phosphoglycerate kinase 2 |
| Synonyms | dJ417L20.2, HEL-S-272, PGKB, PGKPS, phosphoglycerate kinase 2 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Pgk2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- Phosphoglycerate_kinase
- phosphoglycerate kinase
- ATP binding
- protein binding
- hydrophobic domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cilia
- cytosol
- sperm fibrous sheath
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Pgk2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- gluconeogenesis
- sperm motility
- glycolysis
- phosphorylation
Cellular Component
Where in the cell the gene product is active
- nucleus
- extracellular vesicular exosome
- cytosol
- flagellar fibrous sheath
Molecular Function
What the gene product does at the molecular level
- ATP binding
- phosphoglycerate kinase activity
- ADP binding