Nubp2 Gene Summary [Rat]

Predicted to enable iron-sulfur cluster binding activity. Predicted to be involved in iron-sulfur cluster assembly. Predicted to be located in nucleoplasm and spindle pole centrosome. Predicted to be active in cytosol. Orthologous to human NUBP2 (NUBP iron-sulfur cluster assembly factor 2, cytosolic). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Nubp2
Official Name
nucleotide binding protein 2 [Source:RGD Symbol;Acc:1305113]
Ensembl ID
ENSRNOG00000015090
Bio databases IDs NCBI: 287125 Ensembl: ENSRNOG00000015090
Aliases nucleotide binding protein 2
Synonyms CFD1, CIAO6, D17Wsu11e, NBP 2, NUBP1, NUBP iron-sulfur cluster assembly factor 2, NUBP iron-sulfur cluster assembly factor 2, cytosolic, NUBP iron-sulphur cluster assembly factor 2, NUBP iron-sulphur cluster assembly factor 2, cytosolic, nucleotide binding protein 2
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Nubp2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • CobQ/CobB/MinD/ParA nucleotide binding domain
  • nucleotide binding
  • septum site-determining protein MinD
  • NUBPL iron-transfer P-loop NTPase
  • protein binding
  • capsular exopolysaccharide family
  • P-loop containing Nucleoside Triphosphate Hydrolases

Pathways

Biological processes and signaling networks where the Nubp2 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • ocular hypertension
regulated by
  • delta-9-tetrahydrocannabinol
  • MEN1

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Cytoplasm
  • centrosome
  • cytosol
  • nucleoplasm
  • mitotic spindle

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Nubp2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cell projection organization
  • iron-sulfur cluster assembly

Cellular Component

Where in the cell the gene product is active
  • spindle pole centrosome
  • nucleus
  • centriole
  • cilium
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • nucleotide binding
  • ATP binding
  • protein binding
  • metal ion binding
  • 4 iron, 4 sulfur cluster binding
  • iron-sulfur cluster binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.