Tmem14c Gene Summary [Rat]
Predicted to enable protein kinase inhibitor activity. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and regulation of signal transduction by p53 class mediator. Predicted to act upstream of or within cell population proliferation and roof of mouth development. Predicted to be active in nucleolus. Orthologous to human PAK1IP1 (PAK1 interacting protein 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tmem14c |
| Official Name | transmembrane protein 14C [Source:RGD Symbol;Acc:621692] |
| Ensembl ID | ENSRNOG00000015437 |
| Bio databases IDs | |
| Aliases | transmembrane protein 14C |
| Synonyms | bA421M1.6, C6orf53, Cdtw1, HSPC194, MSTP073, NET26, transmembrane protein 14C |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tmem14c often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Transmembrane proteins 14C
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- pH resistant lipid raft fraction
- cellular membrane
- Mitochondria
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Tmem14c gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nitrogen compound transport
- erythrocyte differentiation
- mitochondrial transport
- regulation of heme biosynthetic process
- heme biosynthetic process
Cellular Component
Where in the cell the gene product is active
- mitochondrial membrane
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- protein binding