Gtf2a1l Gene Summary [Rat]

Predicted to be involved in cognition and transcription by RNA polymerase II. Predicted to be located in cytoplasm and male germ cell nucleus. Predicted to be part of transcription factor TFIIA complex. Orthologous to human GTF2A1L (general transcription factor IIA subunit 1 like). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Gtf2a1l
Official Name
general transcription factor 2A subunit 1 like [Source:RGD Symbol;Acc:1308625]
Ensembl ID
ENSRNOG00000016703
Bio databases IDs NCBI: 316711 Ensembl: ENSRNOG00000016703
Aliases general transcription factor 2A subunit 1 like
Synonyms 1700011N16Rik, ALF, general transcription factor 2A subunit 1 like, general transcription factor IIA, 1-like, general transcription factor IIA subunit 1 like, Gtf2a1lf
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gtf2a1l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Transcription factor IIA, alpha/beta subunit
  • transcription regulator
  • transcription co-activator
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • hypertrophic cardiomyopathy
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • Cytoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Gtf2a1l gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cognition
  • positive regulation of transcription, DNA-dependent
  • transcription from RNA polymerase II promoter
  • transcription initiation from RNA polymerase II promoter

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • transcription factor TFIIA complex
  • male germ cell nucleus

Molecular Function

What the gene product does at the molecular level
  • DNA binding
  • protein binding
  • transcription coactivator activity

Gene-Specific Assays for Results You Can Trust

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