Gtf2a1l Gene Summary [Mouse]
Predicted to enable DNA binding activity. Predicted to be involved in cognition and transcription by RNA polymerase II. Located in cytoplasm and male germ cell nucleus. Part of transcription factor TFIIA complex. Is expressed in central nervous system; early conceptus; gonad; and ureter. Orthologous to human GTF2A1L (general transcription factor IIA subunit 1 like). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gtf2a1l |
| Official Name | general transcription factor IIA, 1-like [Source:MGI Symbol;Acc:MGI:1919078] |
| Ensembl ID | ENSMUSG00000024154 |
| Bio databases IDs | |
| Aliases | general transcription factor IIA, 1-like |
| Synonyms | 1700011N16Rik, ALF, general transcription factor 2A subunit 1 like, general transcription factor IIA, 1-like, general transcription factor IIA subunit 1 like, Gtf2a1lf |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gtf2a1l often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Transcription factor IIA, alpha/beta subunit
- transcription regulator
- transcription co-activator
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gtf2a1l gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cognition
- positive regulation of transcription, DNA-dependent
- transcription from RNA polymerase II promoter
- transcription initiation from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- transcription factor TFIIA complex
- male germ cell nucleus
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein binding
- transcription coactivator activity