Mrpl48 Gene Summary [Rat]

Predicted to be located in mitochondrion. Predicted to be part of mitochondrial large ribosomal subunit. Predicted to be active in mitochondrial ribosome. Orthologous to human MRPL48 (mitochondrial ribosomal protein L48). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Mrpl48
Official Name
mitochondrial ribosomal protein L48 [Source:RGD Symbol;Acc:1307576]
Ensembl ID
ENSRNOG00000018042
Bio databases IDs NCBI: 293149 Ensembl: ENSRNOG00000018042
Aliases mitochondrial ribosomal protein L48
Synonyms 1810030E20Rik, 2610028L11Rik, CGI-118, D4ERTD786E, HSPC290, L48MT, LOC102548233, mitochondrial ribosomal protein L48, mL48
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mrpl48 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Ribosomal protein S10p/S20e
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • insulin resistance
  • bipolar disorder
  • major depression
  • liver cancer
  • epithelial cancer
  • hepatocellular carcinoma
  • nicotine withdrawal syndrome
regulated by
  • levodopa
  • AR
role in cell
  • proliferative capacity
  • migratory capacity

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • ribosome
  • Mitochondria
  • mitochondrial matrix
  • mitochondrial inner membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Mrpl48 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mitochondrial translation

Cellular Component

Where in the cell the gene product is active
  • mitochondrion
  • mitochondrial ribosome
  • mitochondrial large ribosomal subunit
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.