Ssh3 Gene Summary [Rat]
Predicted to enable actin binding activity and phosphoprotein phosphatase activity. Predicted to be involved in actin cytoskeleton organization and negative regulation of actin filament polymerization. Predicted to be located in cytoskeleton and nucleus. Predicted to be active in cytoplasm. Orthologous to human SSH3 (slingshot protein phosphatase 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ssh3 |
| Official Name | slingshot protein phosphatase 3 [Source:RGD Symbol;Acc:1308679] |
| Ensembl ID | ENSRNOG00000018878 |
| Bio databases IDs | |
| Aliases | slingshot protein phosphatase 3 |
| Synonyms | slingshot protein phosphatase 3, SSH-3L |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ssh3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Dual specificity phosphatase, catalytic domain
- phosphatase
- DEK C terminal domain
- protein binding
- PTP_DSP_cys
Pathways
Biological processes and signaling networks where the Ssh3 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ssh3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of actin filament polymerization
- actin cytoskeleton organization
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoskeleton
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- phosphoprotein phosphatase activity
- protein binding
- actin binding
- protein tyrosine phosphatase activity
- myosin phosphatase activity