Msln Gene Summary [Rat]
Involved in pancreas development. Located in cell surface and extracellular space. Human ortholog(s) of this gene implicated in ovarian cancer; pancreas disease; pancreatic cancer; and pancreatic ductal carcinoma. Orthologous to human MSLN (mesothelin). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Msln |
| Official Name | mesothelin [Source:RGD Symbol;Acc:69333] |
| Ensembl ID | ENSRNOG00000019445 |
| Bio databases IDs | |
| Aliases | mesothelin |
| Synonyms | mesothelin |
| Species | Rat, Rattus norvegicus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Msln often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- cell surface
- Extracellular Space