Plekhh3 Gene Summary [Rat]

Predicted to be involved in signal transduction. Predicted to be located in cytoskeleton. Orthologous to human PLEKHH3 (pleckstrin homology, MyTH4 and FERM domain containing H3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Plekhh3
Official Name
pleckstrin homology, MyTH4 and FERM domain containing H3 [Source:RGD Symbol;Acc:1304854]
Ensembl ID
ENSRNOG00000020238
Bio databases IDs NCBI: 360634 Ensembl: ENSRNOG00000020238
Aliases pleckstrin homology, MyTH4 and FERM domain containing H3
Synonyms pleckstrin homology domain containing, family H (with MyTH4 domain) member 3, pleckstrin homology, MyTH4 and FERM domain containing H3, RGD1304854
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Plekhh3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Ubl1_cv_Nsp3_N-like
  • PH domain
  • Pleckstrin homology-like domain
  • MyTH4 domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • tonsillitis
  • cataract
regulated by
  • sulforafan

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Plekhh3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • signal transduction

Cellular Component

Where in the cell the gene product is active
  • extracellular space
  • cytoskeleton

Gene-Specific Assays for Results You Can Trust

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