Mcpt1 Gene Summary [Rat]

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in protein maturation. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Mcpt1
Official Name
mast cell protease 1 [Source:RGD Symbol;Acc:3062]
Ensembl ID
ENSRNOG00000020625
Bio databases IDs NCBI: 29266 NCBI: 29265 Ensembl: ENSRNOG00000020625
Aliases mast cell protease 1
Synonyms AV080368, chymase, mast cell protease 1, mast cell protease 1-like 3, Mcp-1, Mcpt1l3, mcpt1l4, rMCP-1, rMCP-2, rMCP-I, rMCP-II, Vch
Species
Rat, Rattus norvegicus
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mcpt1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Trypsin-like serine protease
  • trypsin
  • Tryp_SPc
  • peptidase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • dextran sodium sulfate-induced colitis
  • infection by parasite
regulated by
  • PPARA
  • genistein
  • lipopolysaccharide
  • IL1B
  • beta-estradiol
  • epigallocatechin-gallate
  • methylnitrosourea
  • IL3
  • IL10
  • PPARD
regulates
role in cell
  • apoptosis
  • recruitment
  • abnormal morphology
  • response by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space
  • intracellular space
  • secretory granules