Ap5s1 Gene Summary [Rat]
Predicted to be involved in double-strand break repair via homologous recombination and endosomal transport. Predicted to be located in nucleoplasm. Predicted to be part of AP-type membrane coat adaptor complex. Predicted to be active in cytosol; late endosome; and lysosome. Orthologous to human AP5S1 (adaptor related protein complex 5 subunit sigma 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ap5s1 |
| Official Name | adaptor related protein complex 5 subunit sigma 1 [Source:RGD Symbol;Acc:1561852] |
| Ensembl ID | ENSRNOG00000021249 |
| Bio databases IDs | |
| Aliases | adaptor related protein complex 5 subunit sigma 1 |
| Synonyms | 0610038L13Rik, 2310035K24Rik, adaptor-related protein 5 complex, sigma 1 subunit, adaptor-related protein 5 complex, σ 1 subunit, adaptor related protein complex 5 subunit sigma 1, adaptor related protein complex 5 subunit σ 1, C20orf29, RGD1561852, sigma5 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ap5s1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- AP-5 complex subunit sigma-1
Pathways
Biological processes and signaling networks where the Ap5s1 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- lysosome
- cytosol
- nucleoplasm
- late endosomes
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Ap5s1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- vesicle-mediated transport
- protein transport
- double-strand break repair via homologous recombination
- endosomal transport
Cellular Component
Where in the cell the gene product is active
- late endosome membrane
- AP-type membrane coat adaptor complex
- late endosome
- cytosol
- AP-5 adaptor complex
- lysosomal membrane
- nucleoplasm
- lysosome
Molecular Function
What the gene product does at the molecular level
- protein binding