Ap5m1 Gene Summary [Rat]

Predicted to be involved in endosomal transport. Predicted to be located in membrane. Predicted to be part of AP-type membrane coat adaptor complex. Predicted to be active in cytosol; late endosome; and lysosome. Orthologous to human AP5M1 (adaptor related protein complex 5 subunit mu 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ap5m1
Official Name
adaptor related protein complex 5 subunit mu 1 [Source:RGD Symbol;Acc:1308087]
Ensembl ID
ENSRNOG00000014148
Bio databases IDs NCBI: 305861 Ensembl: ENSRNOG00000014148
Aliases adaptor related protein complex 5 subunit mu 1
Synonyms 4932432K03Rik, adaptor-related protein complex 5, mu 1 subunit, adaptor related protein complex 5 subunit mu 1, C14orf108, Mu5, MuD, MUDENG, RGD1308087
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ap5m1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • AP_MHD_Cterm
  • Adaptor complexes medium subunit family
  • protein binding

Pathways

Biological processes and signaling networks where the Ap5m1 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • renal clear cell adenocarcinoma
  • renal clear cell cancer
regulated by
regulates
role in cell
  • transport
  • swelling
  • swelling in
  • trafficking in
  • tubulation in
  • tubulation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cellular membrane
  • lysosome
  • cytosol
  • late endosomes

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Ap5m1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • vesicle-mediated transport
  • protein transport
  • endosomal transport

Cellular Component

Where in the cell the gene product is active
  • late endosome membrane
  • AP-type membrane coat adaptor complex
  • membrane
  • late endosome
  • cytosol
  • AP-5 adaptor complex
  • lysosomal membrane
  • lysosome

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.