Cabp4 Gene Summary [Rat]

Predicted to enable calcium channel regulator activity and transmembrane transporter binding activity. Predicted to be involved in visual perception. Predicted to act upstream of or within neuron differentiation and phototransduction. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Orthologous to human CABP4 (calcium binding protein 4). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Cabp4
Official Name
calcium binding protein 4 [Source:RGD Symbol;Acc:1306083]
Ensembl ID
ENSRNOG00000022044
Bio databases IDs NCBI: 365394 Ensembl: ENSRNOG00000022044
Aliases calcium binding protein 4
Synonyms calcium binding protein 4, CRSD, CSNB2B
Species
Rat, Rattus norvegicus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cabp4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • EF-hand, calcium binding motif
  • EF-hand domain
  • EF-hand domain pair
  • EF hand
  • EF-hand, calcium binding motif, found in parvalbumin-like EF-hand family
  • calcium ion binding
  • ion channel binding
  • EFh
  • EFh_MICU
  • EFh_PI-PLC
  • Dockerin repeat domains and domains resembling dockerin repeats

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
  • PRKCZ
  • fostriecin
  • okadaic acid
disease
  • Usher syndrome
  • congenital stationary night blindness type 2B
  • cone dystrophy
  • rotator cuff injury
  • cone-rod dystrophy
  • retinal dystrophy
  • Forsius-Eriksson type ocular albinism
  • achromatopsia

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • cytosol
  • synapse
  • axon terminals

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Cabp4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • retinal bipolar neuron differentiation
  • photoreceptor cell morphogenesis
  • signal transduction
  • visual perception
  • retinal cone cell development
  • phototransduction

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • terminal button
  • cytosol
  • synapse
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • calcium ion binding
  • calcium channel regulator activity
  • ion channel binding

Gene-Specific Assays for Results You Can Trust

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