Cplane2 Gene Summary [Rat]
Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in exocytosis and protein transport. Predicted to act upstream of or within several processes, including axoneme assembly; endocardial cushion fusion; and regulation of smoothened signaling pathway. Predicted to be located in centriole; ciliary basal body; and ciliary transition zone. Predicted to be active in ciliary base. Orthologous to human CPLANE2 (ciliogenesis and planar polarity effector complex subunit 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cplane2 |
| Official Name | ciliogenesis and planar polarity effector 2 [Source:RGD Symbol;Acc:1561421] |
| Ensembl ID | ENSRNOG00000023346 |
| Bio databases IDs | |
| Aliases | ciliogenesis and planar polarity effector 2 |
| Synonyms | 6330545A04Rik, b2b2804Clo, b2b2827Clo, C1orf89, ciliogenesis and planar polarity effector 2, ciliogenesis and planar polarity effector complex subunit 2, Gm723, RGD1561421, RSG1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cplane2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GTP binding
- GTPase
- enzyme
- protein binding
- Ras of Complex, Roc, domain of DAPkinase
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ciliary transition zone
- basal bodies
- centriole
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cplane2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cilium morphogenesis
- limb development
- protein transport
- protein localization
- smoothened signaling pathway
- axoneme assembly
- endocardial cushion fusion
- exocytosis
- regulation of smoothened signaling pathway
- regulation of vesicle fusion
- protein processing
- regulation of exocytosis
Cellular Component
Where in the cell the gene product is active
- centriole
- cytoplasm
- cilium basal body
- ciliary transition zone
Molecular Function
What the gene product does at the molecular level
- GTP binding
- protein binding
- GTPase activity