Marchf11 Gene Summary [Rat]

Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in cytoplasmic vesicle membrane and endomembrane system. Orthologous to human MARCHF11 (membrane associated ring-CH-type finger 11). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Marchf11
Official Name
membrane associated ring-CH-type finger 11 [Source:RGD Symbol;Acc:1559945]
Ensembl ID
ENSRNOG00000024461
Bio databases IDs NCBI: 499558 Ensembl: ENSRNOG00000024461
Aliases membrane associated ring-CH-type finger 11
Synonyms 40603.00, 9630025C22, MARCH11, MARCH-XI, membrane associated ring-CH-type finger 11, RGD1559945, RNF226
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Marchf11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • RING finger (Really Interesting New Gene) domain and U-box domain superfamily

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • colorectal cancer
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Marchf11 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein ubiquitination

Cellular Component

Where in the cell the gene product is active
  • cytoplasmic vesicle membrane

Molecular Function

What the gene product does at the molecular level
  • ubiquitin-protein ligase activity
  • zinc ion binding

Gene-Specific Assays for Results You Can Trust

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