Tpte2 Gene Summary [Rat]
Predicted to enable phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity. Predicted to be involved in monoatomic ion transmembrane transport. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytosol. Orthologous to several human genes including TPTE2 (transmembrane phosphoinositide 3-phosphatase and tensin homolog 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tpte2 |
| Official Name | transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 [Source:RGD Symbol;Acc:1305825] |
| Ensembl ID | ENSRNOG00000024837 |
| Bio databases IDs | |
| Aliases | transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 |
| Synonyms | LOC102551183, Pten2, Tpte2, transmembrane phosphatase with tensin homology, transmembrane phosphoinositide 3-phosphatase and tensin homolog 2, Vsp |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tpte2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- C2 domain of PTEN tumour-suppressor protein
- PTP_DSP_cys
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
- endoplasmic reticulum membrane